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1

Structural basis for the sheddase function of human meprin metalloproteinase at the plasma membrane

Arolas, J. L., Broder, C., Jefferson, T., Guevara, T., Sterchi, E. E., Bode, W., Stocker, W., Becker-Pauly, C., Gomis-Ruth, F. X.

Journal:

Proceedings of the National Academy of Sciences

Year:

2012

Language:

english

File:

PDF, 979 KB

english, 2012

2

Structural Evidence for Standard-Mechanism Inhibition in Metallopeptidases from a Complex Poised to Resynthesize a Peptide Bond

Dr. Joan L. Arolas, Dr. Tiago O. Botelho, Prof. Dr. Andreas Vilcinskas, Prof. Dr. F. Xavier Gomis-Rüth

Journal:

Angewandte Chemie

Year:

2011

Language:

english

File:

PDF, 1.30 MB

english, 2011

3

Structural Evidence for Standard-Mechanism Inhibition in Metallopeptidases from a Complex Poised to Resynthesize a Peptide Bond

Dr. Joan L. Arolas, Dr. Tiago O. Botelho, Prof. Dr. Andreas Vilcinskas, Prof. Dr. F. Xavier Gomis-Rüth

Journal:

Angewandte Chemie International Edition

Year:

2011

Language:

english

File:

PDF, 1.28 MB

english, 2011

4

Bacterial conjugation: a two-step mechanism for DNA transport

Matxalen Llosa, F. Xavier Gomis-Rüth, Miquel Coll, Fernando de la Cruz

Journal:

Molecular Microbiology

Year:

2002

Language:

english

File:

PDF, 81 KB

english, 2002

5

The role of exon 5 in fibroblast collagenase (MMP-1) substrate specificity and inhibitor selectivity

Vera Knäuper, Margaret L. Patterson, Franz X. Gomis-Rüth, Bryan Smith, Alan Lyons, Andrew J. P. Docherty, Gillian Murphy

Journal:

Year:

2001

Language:

english

File:

PDF, 528 KB

english, 2001

6

The metzincins — Topological and sequential relations between the astacins, adamalysins, serralysins, and matrixins (collagenases) define a super family of zinc-peptidases

Walter Stöcker, Frank Grams, Peter Reinemer, Wolfram Bode, Ulrich Baumann, Franz-Xaver Gomis-Rüth, David B. Mckay

Journal:

Protein Science

Year:

1995

Language:

english

File:

PDF, 7.38 MB

english, 1995

7

Structures of adamalysin II with peptidic inhibitors. Implications for the design of tumor necrosis factor α convertase inhibitors

F. Xavier Gomis-Rüth, Edgar F. Meyer, Lawrence F. Kress, Vincenzo Politi

Journal:

Protein Science

Year:

1998

Language:

english

File:

PDF, 3.85 MB

english, 1998

8

The eight-cysteine motif, a versatile structure in plant proteins

Matilde José-Estanyol, F.Xavier Gomis-Rüth, Pere Puigdomènech

Journal:

Plant Physiology and Biochemistry

Year:

2004

Language:

english

File:

PDF, 744 KB

english, 2004

9

The molecular analysis of Trypanosoma cruzi metallocarboxypeptidase 1 provides insight into fold and substrate specificity

Gabriela Niemirowicz, Daniel Fernández, Maria Solà, Juan J. Cazzulo, Francesc X. Avilés, F. Xavier Gomis-Rüth

Journal:

Molecular Microbiology

Year:

2008

Language:

english

File:

PDF, 1.13 MB

english, 2008

10

The structure of the catalytic domain of Tannerella forsythia karilysin reveals it is a bacterial xenologue of animal matrix metalloproteinases

Núria Cerdà-Costa, Tibisay Guevara, Abdulkarim Y. Karim, Miroslaw Ksiazek, Ky-Anh Nguyen, Joan L. Arolas, Jan Potempa, F. Xavier Gomis-Rüth

Journal:

Molecular Microbiology

Year:

2011

Language:

english

File:

PDF, 1.43 MB

english, 2011

11

Insights into the molecular inactivation mechanism of human activated thrombin-activatable fibrinolysis inhibitor

L. SANGLAS, J. L. AROLAS, Z. VALNICKOVA, F. X. AVILES, J. J. ENGHILD, F. X. GOMIS-RÜTH

Journal:

Journal of Thrombosis and Haemostasis

Year:

2010

Language:

english

File:

PDF, 655 KB

english, 2010

12

Staphylococcal methicillin resistance: fine focus on folds and functions

Goretti Mallorquí-Fernández, Aniebrys Marrero, Sonia García-Piquè, Raquel García-Castellanos, F.Xavier Gomis-Rüth

Journal:

FEMS Microbiology Letters

Year:

2004

Language:

english

File:

PDF, 346 KB

english, 2004

13

Insights into MMP-TIMP Interactions

WOLFRAM BODE, CARLOS FERNANDEZ-CATALAN, FRANK GRAMS, FRANZ-XAVER GOMIS-RÜTH, HIDEAKI NAGASE, HARALD TSCHESCHE, KLAUS MASKOS

Journal:

Annals of the New York Academy of Sciences

Year:

1999

Language:

english

File:

PDF, 1.47 MB

english, 1999

14

10.1038/35054586

Gomis-Rüth, F. Xavier, Moncalián, Gabriel, Pérez-Luque, Rosa, González, Ana, Cabezón, Elena, de la Cruz, Fernando, Coll, Miquel

Journal:

Year:

2001

Language:

english

File:

PDF, 567 KB

english, 2001

15

Structure of astacin and implications for activation of astacins and zinc-ligation of collagenases

Bode, W., Gomis-Rüth, F. X., Huber, R., Zwilling, R., Stöcker, W.

Journal:

Year:

1992

File:

PDF, 728 KB

1992

16

Plasmid replication initiator RepB forms a hexamer reminiscent of ring helicases and has mobile nuclease domains

Boer, D Roeland, Ruíz-Masó, José A, López-Blanco, José R, Blanco, Alexander G, Vives-Llàcer, Mireia, Chacón, Pablo, Usón, Isabel, Gomis-Rüth, F Xavier, Espinosa, Manuel, Llorca, Oscar

Journal:

The EMBO Journal

Year:

2009

Language:

english

File:

PDF, 2.17 MB

english, 2009

17

Macrophage elastase kills bacteria within murine macrophages

Houghton, A. McGarry, Hartzell, William O., Robbins, Clinton S., Gomis-Rüth, F. Xavier, Shapiro, Steven D.

Journal:

Year:

2009

Language:

english

File:

PDF, 646 KB

english, 2009

18

Recognition and processing of the origin of transfer DNA by conjugative relaxase TrwC

Guasch, Alicia, Lucas, María, Moncalián, Gabriel, Cabezas, Matilde, Pérez-Luque, Rosa, Gomis-Rüth, F Xavier, de la Cruz, Fernando, Coll, Miquel

Journal:

Natural Structural Biology

Year:

2003

Language:

english

File:

PDF, 850 KB

english, 2003

19

Corrigendum: Recognition and processing of the origin of transfer DNA by conjugative relaxase TrwC

Guasch, Alicia, Lucas, María, Moncalián, Gabriel, Cabezas, Matilde, Pérez-Luque, Rosa, Gomis-Rüth, F Xavier, de la Cruz, Fernando, Coll, Miquel

Journal:

Nature Structural and Molecular Biology

Year:

2004

Language:

english

File:

PDF, 49 KB

english, 2004

20

Structural aspects of the metzincin clan of metalloendopeptidases

F. Xavier Gomis-Rüth

Journal:

Molecular Biotechnology

Year:

2003

Language:

english

File:

PDF, 1.42 MB

english, 2003

21

The structure of plasmid-encoded transcriptional repressor CopG unliganded and bound to its operator

Gomis-Ruth, F.X.

Journal:

The EMBO Journal

Year:

1998

Language:

english

File:

PDF, 950 KB

english, 1998

22

Matrix metalloproteinases: Fold and function of their catalytic domains

Cynthia Tallant, Aniebrys Marrero, F.Xavier Gomis-Rüth

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Year:

2010

Language:

english

File:

PDF, 1.41 MB

english, 2010

23

Plasticity of Polarization: Changing Dendrites into Axons in Neurons Integrated in Neuronal Circuits

Susana Gomis-Rüth, Corette J. Wierenga, Frank Bradke

Journal:

Current Biology

Year:

2008

Language:

english

File:

PDF, 1.50 MB

english, 2008

24

Cut and move: protein machinery for DNA processing in bacterial conjugation

F Xavier Gomis-Rüth, Miquel Coll

Journal:

Current Opinion in Structural Biology

Year:

2006

Language:

english

File:

PDF, 1.49 MB

english, 2006

25

Tandem DNA Recognition by PhoB, a Two-Component Signal Transduction Transcriptional Activator

Alexandre G. Blanco, Maria Sola, F.Xavier Gomis-Rüth, Miquel Coll

Journal:

Year:

2002

Language:

english

File:

PDF, 738 KB

english, 2002

26

The Matrix Protein VP40 from Ebola Virus Octamerizes into Pore-like Structures with Specific RNA Binding Properties

F.Xavier Gomis-Rüth, Andréa Dessen, Joanna Timmins, Andreas Bracher, Larissa Kolesnikowa, Stephan Becker, Hans-Dieter Klenk, Winfried Weissenhorn

Journal:

Year:

2003

Language:

english

File:

PDF, 475 KB

english, 2003

27

A novel strategy for inhibition of α-amylases: yellow meal worm α-amylase in complex with the Ragi bifunctional inhibitor at 2.5 å resolution

Stefan Strobl, Klaus Maskos, Georg Wiegand, Robert Huber, F Xavier Gomis-Rüth, Rudi Glockshuber

Journal:

Year:

1998

Language:

english

File:

PDF, 1018 KB

english, 1998

28

Cutting at the right place : The importance of selective limited proteolysis in the activation of proproteinase E

F. Xavier Gomis-Rüth, Mariola Gómez-Ortiz, Josep Vendrell, Salvador Ventura, Wolfram Bode, Robert Huber, Francesc X. Avilés

Journal:

Year:

1998

Language:

english

File:

PDF, 1.21 MB

english, 1998

29

Implications of the three-dimensional structure of astacin for the structure and function of the astacin family of zinc-endopeptidases

Walter STÖCKER, Franz-Xaver GOMIS-RÜTH, Wolfram BODE, Robert ZWILLING

Journal:

Year:

1993

Language:

english

File:

PDF, 2.31 MB

english, 1993

30

1.8-Å Crystal Structure of the Catalytic Domain of Human Neutrophil Collagenase (Matrix Metalloproteinase-8) Complexed with a Peptidomimetic Hydroxamate Primed-Side Inhibitor with a Distinct Selectivity Profile

Michael Betz, Philip Huxley, Stephen J. Davies, Yasmeen Mushtaq, Michael Pieper, Harald Tschesche, Wolfram Bode, F. Xavier Gomis-Rüth

Journal:

Year:

1997

Language:

english

File:

PDF, 915 KB

english, 1997

31

Refined 1·8 Å X-ray Crystal Structure of Astacin, a Zinc-endopeptidase from the Crayfish Astacus astacus L.: Structure Determination, Refinement, Molecular Structure and Comparison with Thermolysin

F.X. Gomis-Rüth, W. Stöcker, R. Huber, R. Zwilling, W. Bode

Journal:

Journal of Molecular Biology

Year:

1993

File:

PDF, 1.30 MB

1993

32

Refined 2·0 Å X-ray Crystal Structure of the Snake Venom Zinc-endopeptidase Adamalysin II: Primary and Tertiary Structure Determination, Refinement, Molecular Structure and Comparison with Astacin, Collagenase and Thermolysin

F.X. Gomis-Rüth, L.F. Kress, J. Kellermann, I. Mayr, X. Lee, R. Huber, W. Bode

Journal:

Journal of Molecular Biology

Year:

1994

File:

PDF, 1.78 MB

1994

33

The Helping Hand of Collagenase-3 (MMP-13): 2.7 Å Crystal Structure of its C-terminal Haemopexin-like Domain

F.X. Gomis-Rüth, U. Gohlke, M. Betz, V. Knäuper, G. Murphy, C. López-Otı́n, W. Bode

Journal:

Journal of Molecular Biology

Year:

1996

Language:

english

File:

PDF, 2.72 MB

english, 1996

34

Crystal structure of an oligomer of proteolytic zymogens: detailed conformational analysis of the bovine ternary complex and implications for their activation

F.X Gomis-Rüth, M Gómez-Ortiz, J Vendrell, S Ventura, W Bode, R Huber, F.X Avilés

Journal:

Journal of Molecular Biology

Year:

1997

Language:

english

File:

PDF, 782 KB

english, 1997

35

Crystal structure of yellow meal worm α-amylase at 1.64 Å resolution

Stefan Strobl, Klaus Maskos, Michael Betz, Georg Wiegand, Robert Huber, F.Xavier Gomis-Rüth, Rudi Glockshuber

Journal:

Journal of Molecular Biology

Year:

1998

Language:

english

File:

PDF, 729 KB

english, 1998

36

The three-dimensional structure of human RNase 4, unliganded and complexed with d(up), reveals the basis for its uridine selectivity

Simon S Terzyan, Rosa Peracaula, Rafael de Llorens, Yoshiaki Tsushima, Hidenori Yamada, Masaharu Seno, F.Xavier Gomis-Rüth, Miquel Coll

Journal:

Journal of Molecular Biology

Year:

1999

Language:

english

File:

PDF, 621 KB

english, 1999

37

Three-dimensional crystal structure of the transcription factor PhoB receiver domain

Maria Solà, F.Xavier Gomis-Rüth, Luis Serrano, Ana González, Miquel Coll

Journal:

Journal of Molecular Biology

Year:

1999

Language:

english

File:

PDF, 2.86 MB

english, 1999

38

Three-dimensional crystal structure of human eosinophil cationic protein (RNase 3) at 1.75 Å resolution

Goretti Mallorquı́-Fernández, Joan Pous, Rosa Peracaula, Joan Aymamı́, Takashi Maeda, Hiroko Tada, Hidenori Yamada, Masaharu Seno, Rafael de Llorens, F.Xavier Gomis-Rüth, Miquel Coll

Journal:

Journal of Molecular Biology

Year:

2000

Language:

english

File:

PDF, 585 KB

english, 2000

39

Plasmid transcriptional repressor CopG oligomerises to render helical superstructures unbound and in complexes with oligonucleotides

M Costa, M Solà, G del Solar, R Eritja, A.M Hernández-Arriaga, M Espinosa, F.X Gomis-Rüth, M Coll

Journal:

Journal of Molecular Biology

Year:

2001

Language:

english

File:

PDF, 1.07 MB

english, 2001

40

Detailed architecture of a DNA translocating machine: the high-resolution structure of the bacteriophage φ29 connector particle

Alicia Guasch, Joan Pous, Borja Ibarra, F.Xavier Gomis-Rüth, José Marı́a Valpuesta, Natalia Sousa, José L Carrascosa, Miquel Coll

Journal:

Journal of Molecular Biology

Year:

2002

Language:

english

File:

PDF, 795 KB

english, 2002

41

Astacins, serralysins, snake venom and matrix metalloproteinases exhibit identical zinc-binding environments (HEXXHXXGXXH and Met-turn) and topologies and should be grouped into a common family, the ‘metzincins’

Wolfram Bode, Franz-Xaver Gomis-Rüth, Walter Stöckler

Journal:

Year:

1993

Language:

english

File:

PDF, 791 KB

english, 1993

42

Crystallization and preliminary X-ray analysis of the ternary complex of procarboxypeptidase A from bovine pancreas

F.X. Gomis-Rüth, M. Gómez, S. Ventura, J. Vendrell, F.X. Avilés

Journal:

Year:

1995

Language:

english

File:

PDF, 320 KB

english, 1995

43

Crystal structure analysis, refinement and enzymatic reaction mechanism of N-carbamoylsarcosine amidohydrolase from Arthrobacter sp. at 2·0Åresolution

Maria Joa˜o Roma˜o, Dusan Turk, Franz-Xaver Gomis-Rüth, Robert Huber, Günther Schumacher, Hans Möllering, Lorenz Rüssmann

Journal:

Journal of Molecular Biology

Year:

1992

Language:

english

File:

PDF, 2.10 MB

english, 1992

44

Substrate specificity of a metalloprotease of the pappalysin family revealed by an inhibitor and a product complex

Raquel García-Castellanos, CynthiaTallant, Aniebrys Marrero, Maria Solà, Ulrich Baumann, F. Xavier Gomis-Rüth

Journal:

Archives of Biochemistry and Biophysics

Year:

2007

Language:

english

File:

PDF, 3.49 MB

english, 2007

45

A standard orientation for metallopeptidases

F. Xavier Gomis-Rüth, Tiago O. Botelho, Wolfram Bode

Journal:

Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics

Year:

2012

Language:

english

File:

PDF, 1.76 MB

english, 2012

46

Staphylococcal methicillin resistance: fine focus on folds and functions

Goretti Mallorquı́-Fernández, Aniebrys Marrero, Sonia Garcı́a-Piquè, Raquel Garcı́a-Castellanos, F.Xavier Gomis-Rüth

Journal:

FEMS Microbiology Letters

Year:

2004

Language:

english

File:

PDF, 349 KB

english, 2004

47

Unbound and Acylated Structures of the MecR1 Extracellular Antibiotic-sensor Domain Provide Insights into the Signal-transduction System that Triggers Methicillin Resistance

Aniebrys Marrero, Goretti Mallorquí-Fernández, Tibisay Guevara, Raquel García-Castellanos, F. Xavier Gomis-Rüth

Journal:

Journal of Molecular Biology

Year:

2006

Language:

english

File:

PDF, 970 KB

english, 2006

48

The X-ray Crystal Structures of Two Constitutively Active Mutants of the Escherichia coli PhoB Receiver Domain Give Insights into Activation

Raquel Arribas-Bosacoma, Soo-Ki Kim, Cristina Ferrer-Orta, Alexandre G. Blanco, Pedro J.B. Pereira, F. Xavier Gomis-Rüth, Barry L. Wanner, Miquel Coll, Maria Solà

Journal:

Journal of Molecular Biology

Year:

2007

Language:

english

File:

PDF, 1.19 MB

english, 2007

49

Structure–Function Analysis of the Short Splicing Variant Carboxypeptidase Encoded by Drosophila melanogaster silver

Sebastián Tanco, Joan L. Arolas, Tibisay Guevara, Julia Lorenzo, Francesc X. Avilés, F. Xavier Gomis-Rüth

Journal:

Journal of Molecular Biology

Year:

2010

Language:

english

File:

PDF, 1.65 MB

english, 2010

50

Structure of Activated Thrombin-Activatable Fibrinolysis Inhibitor, a Molecular Link between Coagulation and Fibrinolysis

Laura Sanglas, Zuzana Valnickova, Joan L. Arolas, Irantzu Pallarés, Tibisay Guevara, Maria Solà, Torsten Kristensen, Jan J. Enghild, Francesc X. Aviles, F. Xavier Gomis-Rüth

Journal:

Year:

2008

Language:

english

File:

PDF, 1.22 MB

english, 2008

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